United States securities and exchange commission logo April 29, 2021 Steven Cobourn Chief Financial Officer NextCure, Inc. 9000 Virginia Manor Road, Suite 200 Beltsville, MD 20705 Re: NextCure, Inc. Form 10-K for the Fiscal Year Ended December 31, 2020 Filed March 4, 2021 File No. 001-38905 Dear Mr. Cobourn: We have completed our review of your filings. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Sincerely, Division of Corporation Finance Office of Life Sciences