November 6, 2019 Michael Richman Chief Executive Officer NextCure, Inc. 9000 Virginia Manor Road, Suite 200 Beltsville, Maryland 20705 Re: NextCure, Inc. Draft Registration Statement on Form S-1 Submitted on October 29, 2019 CIK No. 0001661059 Dear Mr. Richman: This is to advise you that we do not intend to review your registration statement. We request that you publicly file your registration statement no later than 48 hours prior to the requested effective date and time. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Gregory Dundas, Attorney Adviser, at (202) 551-3436 with any questions. Sincerely, Division of Corporation Finance Office of Life Sciences cc: William Intner, Esq.