Cover Abstract Statement [Table] Statement [Line Items] Document Type Document Annual Report Document Period End Date Document Transition Report Securities Act File Number Entity Registrant Name Entity Central Index Key Entity Incorporation, State or Country Code Entity Tax Identification Number Entity Address, Address Line One Entity Address, City or Town Entity Address, State or Province Entity Address, Postal Zip Code City Area Code Local Phone Number Title of 12(b) Security Trading Symbol Security Exchange Name Entity Well-known Seasoned Issuer Entity Voluntary Filers Entity Current Reporting Status Entity Interactive Data Current Entity Filer Category Entity Small Business Entity Emerging Growth Company ICFR Auditor Attestation Flag Document Financial Statement Error Correction [Flag] Entity Shell Company Entity Public Float Entity Common Stock, Shares Outstanding Documents Incorporated by Reference [Text Block] Current Fiscal Year End Date Document Fiscal Year Focus Document Fiscal Period Focus Amendment Flag Auditor Name Auditor Firm ID Auditor Location BALANCE SHEETS Assets [Abstract] Assets Assets, Current [Abstract] Current assets: Cash and Cash Equivalents, at Carrying Value Cash and cash equivalents Debt Securities, Available-for-Sale, Excluding Accrued Interest, Current Marketable securities Prepaid Expense and Other Assets, Current Prepaid expenses and other current assets Assets, Current Total current assets Property, Plant and Equipment, Net Property and equipment, net Property and equipment, net Operating Lease, Right-of-Use Asset Right of use assets Other Assets, Noncurrent Other assets Assets Total assets Liabilities and Equity [Abstract] Liabilities and Stockholders' Equity Liabilities, Current [Abstract] Current liabilities: Accounts Payable, Current Accounts payable Carrying value as of the balance sheet date of obligations incurred and payable, pertaining to costs that are statutory in nature, are incurred on contractual obligations, or accumulate over time and for which invoices have not yet been received or will not be rendered. Examples include taxes, interest, rent and utilities and amount of liabilities classified as other, due within one year or the normal operating cycle, if longer. Accrued and Other Liabilities Current Accrued liabilities and other liabilities Total accrued liabilities and other liabilities Liabilities, Current Total current liabilities Operating Lease, Liability, Noncurrent Lease liabilities, long term Other Liabilities, Noncurrent Other long-term liabilities Liabilities Total liabilities Equity, Attributable to Parent [Abstract] Stockholders' equity: Preferred Stock, Value, Issued Preferred stock, par value of $0.001 per share; 10,000,000 shares authorized at December 31, 2025 and December 31, 2024; No shares issued and outstanding at December 31, 2025 and December 31, 2024 Common Stock, Value, Issued Common stock, par value of $0.001 per share; 100,000,000 shares authorized at December 31, 2025 and December 31, 2024; 3,505,621 and 2,333,896 shares issued and outstanding at December 31, 2025 and December 31, 2024, respectively Additional Paid in Capital Additional paid-in capital Accumulated Other Comprehensive Income (Loss), Net of Tax Accumulated other comprehensive income Retained Earnings (Accumulated Deficit) Accumulated deficit Equity, Attributable to Parent Balance at the end Balance at the beginning Total stockholders' equity Liabilities and Equity Total liabilities and stockholders' equity Preferred Stock, Par or Stated Value Per Share Preferred stock, par value per share Preferred Stock, Shares Authorized Preferred stock, number of shares authorized Preferred Stock, Shares Issued Preferred stock, shares issued Preferred Stock, Shares Outstanding Preferred stock, shares outstanding Common Stock, Par or Stated Value Per Share Common stock, par value per share Common Stock, Shares Authorized Common stock, number of shares authorized Common Stock, Shares, Issued Common stock, shares issued Common Stock, Shares, Outstanding Balance at the end (in shares) Balance at the beginning (in shares) Common stock, shares outstanding STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS Operating Expenses [Abstract] Operating expenses: Research and Development Expense Research and development Total R&D General and Administrative Expense General and administrative Total G&A Restructuring Costs and Asset Impairment Charges Restructuring and asset impairment charges Operating Expenses Total operating expenses Operating Income (Loss) Loss from operations Other Nonoperating Income (Expense) Other income, net Net loss Net loss Not available. Earnings Per Shares Basic And Diluted Abstract Net loss per common share Earnings Per Share, Basic Basic (in dollars per share) Earnings Per Share, Diluted Diluted (in dollars per share) Not available. Earnings Per Shares Basic And Diluted Other Disclosures Abstract Weighted average shares outstanding Weighted Average Number of Shares Outstanding, Basic Basic (in shares) Weighted Average Number of Shares Outstanding, Diluted Diluted (in shares) Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent [Abstract] Comprehensive loss: OCI, Debt Securities, Available-for-Sale, Unrealized Holding Gain (Loss), before Adjustment, after Tax Unrealized gain on marketable securities Comprehensive Income (Loss), Net of Tax, Attributable to Parent Total comprehensive loss STATEMENTS OF STOCKHOLDERS' EQUITY Equity Components [Axis] Equity Component [Domain] Common Stock [Member] Common Stock Additional Paid-in Capital [Member] Additional Paid-in Capital AOCI Attributable to Parent [Member] Accumulated Other Comprehensive (Loss) Income Retained Earnings [Member] Accumulated Deficit Sale of Stock [Axis] Sale of Stock [Domain] Represents the information pertaining to at-the-market sales. At The Market [Member] At-the-market sales Private Placement [Member] Private Placement Increase (Decrease) in Stockholders' Equity [Roll Forward] Increase (Decrease) in Stockholders' Deficit APIC, Share-Based Payment Arrangement, Increase for Cost Recognition Stock based compensation Stock Issued During Period, Value, Stock Options Exercised Exercise of stock options Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period Exercised (in shares) Exercise of stock options (in shares) Stock Issued During Period, Value, Employee Stock Purchase Plan Issuance of shares under ESPP Stock Issued During Period, Shares, Employee Stock Purchase Plans Issuance of shares under ESPP (in shares) Stock Issued During Period, Value, New Issues Issuances of shares, net of expenses Stock Issued During Period, Shares, New Issues Issuances of shares, net of expenses (in shares) Stock issued Value of stock issued as a result of the exercise of pre-funded warrants. Stock Issued During Period, Value, Exercise Of Pre-Funded Warrants Exercise of pre-funded warrants Number of shares issued during the period as a result of exercise of pre-funded warrants. Stock Issued During Period, Shares, Exercise Of Pre-Funded Warrants Exercise of pre-funded warrants (in shares) Adjusted amount after tax, before reclassification adjustments, of unrealized holding gain (loss) on available-for-sale securities. Other Comprehensive Income Unrealized Holding Gain Loss On Securities Arising During Period Net Of Tax Adjusted Unrealized (loss) gain on marketable securities, net of tax Stock Issued During Period, Shares, Reverse Stock Splits Reverse Split (1 for 12) adjustment (in shares) Payments of Stock Issuance Costs Issuance costs OCI, Debt Securities, Available-for-Sale, Unrealized Holding Gain (Loss), before Adjustment, Tax Unrealized gain (loss) on marketable securities, tax expense (benefit) Stockholders' Equity Note, Stock Split, Conversion Ratio Reverse stock split ratio STATEMENTS OF CASH FLOWS Net Cash Provided by (Used in) Operating Activities [Abstract] Cash flows from operating activities: Net Income (Loss), Including Portion Attributable to Noncontrolling Interest Net loss Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract] Adjustments to reconcile net loss to net cash used in operating activities: The aggregate expense recognized in the current period that allocates the cost of tangible assets, intangible assets, or depleting assets to periods that benefit from use of the assets and other items. Depreciation Depletion And Amortization And Other Depreciation and amortization Accretion (Amortization) of Discounts and Premiums, Investments Amortization of premiums and discounts on marketable securities Share-Based Payment Arrangement, Noncash Expense Stock-based compensation Tangible Asset Impairment Charges Asset impairment Impairment charges Represents the amount of noncash operating lease expense. Noncash Operating Lease Expense Noncash operating lease expense Increase (Decrease) in Operating Capital [Abstract] Changes in operating assets and liabilities: Increase (Decrease) in Prepaid Expense and Other Assets Prepaid expenses and other assets Increase (Decrease) in Accounts Payable Accounts payable The increase (decrease) during the reporting period in the aggregate amount of expenses incurred but not yet paid and Other Current Liabilities. Increase Decrease In Accrued And Other Current Liabilities Accrued liabilities and other liabilities Increase (Decrease) in Operating Lease Liability Lease liabilities Increase (Decrease) in Other Noncurrent Liabilities Other long-term liabilities Net Cash Provided by (Used in) Operating Activities Net cash used in operating activities Net Cash Provided by (Used in) Investing Activities [Abstract] Cash flows from investing activities: Proceeds from Sale and Maturity of Marketable Securities Sales and maturities of marketable securities Payments to Acquire Marketable Securities Purchases of marketable securities Payments to Acquire Property, Plant, and Equipment Purchases of property and equipment Net Cash Provided by (Used in) Investing Activities Net cash provided by investing activities Net Cash Provided by (Used in) Financing Activities [Abstract] Cash flows from financing activities: Proceeds from Issuance of Common Stock Proceeds from issuance of common stock Proceeds from Stock Options Exercised Proceeds from exercise of stock options Proceeds from Stock Plans Proceeds from shares issued under ESPP Net Cash Provided by (Used in) Financing Activities Net cash provided by financing activities Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate Effect Net increase (decrease) in cash and cash equivalents Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents Cash and cash equivalents - end of period Cash and cash equivalents - beginning of period Supplemental Cash Flow Information [Abstract] Supplemental disclosures of cash flow information: Interest Paid, Excluding Capitalized Interest, Operating Activities Cash paid for interest Nature of the Business and Basis of Presentation Organization, Consolidation and Presentation of Financial Statements Disclosure [Text Block] Nature of the Business and Basis of Presentation Summary of Significant Accounting Policies Significant Accounting Policies [Text Block] Summary of Significant Accounting Policies No definition available. License Agreement The entire disclosure for licensing agreements. License Agreement [Text Block] License Agreement Not available. Collaboration Agreements Collaborative Arrangement Disclosure [Text Block] Collaboration Agreements Marketable Securities Investments in Debt and Marketable Equity Securities (and Certain Trading Assets) Disclosure [Text Block] Marketable Securities Fair Value Measurements Fair Value Disclosures [Text Block] Fair Value Measurements Property and Equipment, Net Property, Plant and Equipment Disclosure [Text Block] Property and Equipment, Net Accrued Liabilities and Other Liabilities Accounts Payable and Accrued Liabilities Disclosure [Text Block] Accrued Liabilities and Other Liabilities Leases Lessee, Operating Leases [Text Block] Leases Commitments and Contingencies. Commitments and Contingencies Disclosure [Text Block] Commitments and Contingencies Preferred Stock. Preferred Stock [Text Block] Preferred Stock Common Stock. The entire disclosure for terms, amounts, nature of changes, rights and privileges, dividends, and other matters related to common stock. Common Stock [Text Block] Common Stock Stock-Based Compensation Share-Based Payment Arrangement [Text Block] Stock-Based Compensation Restructuring and Asset Impairment Restructuring and Related Activities Disclosure [Text Block] Restructuring and Asset Impairment Segment Information Segment Reporting Disclosure [Text Block] Segment Information Net Loss per Share Attributable to Common Stockholders Earnings Per Share [Text Block] Net Loss per Share Attributable to Common Stockholders Income Taxes Income Tax Disclosure [Text Block] Income Taxes Employee Benefit Plan Retirement Benefits [Text Block] Employee Benefit Plan Subsequent Event Subsequent Events [Text Block] Subsequent Events Basis of Accounting, Policy [Policy Text Block] Basis of Presentation Disclosure of accounting policy for going concern. Going Concern Policy [Policy Text Block] Liquidity and Going Concern Use of Estimates, Policy [Policy Text Block] Use of Estimates Cash and Cash Equivalents, Policy [Policy Text Block] Cash and Cash Equivalents Marketable Securities, Policy [Policy Text Block] Marketable Securities Concentration Risk, Credit Risk, Policy [Policy Text Block] Concentration of Credit Risk Fair Value of Financial Instruments, Policy [Policy Text Block] Fair Value of Financial Instruments Property, Plant and Equipment, Policy [Policy Text Block] Property and Equipment, Net Separation of Lease and Nonlease Components [Policy Text Block] Leases Impairment or Disposal of Long-Lived Assets, Policy [Policy Text Block] Long-Lived Asset Impairment Assessments Disclosure of accounting policy for Pre-Funded Warrants. Pre-Funded Warrants Policy [Policy Text Block] Pre-Funded Warrants Stockholders' Equity Note, Redeemable Preferred Stock, Issue, Policy [Policy Text Block] Preferred Stock Collaborative Arrangement, Accounting Policy [Policy Text Block] Collaboration Arrangements Research and Development Expense, Policy [Policy Text Block] Research and Development Costs, Including Clinical Trial Accruals and Acquired in Process Research and Development Costs Associated with Exit or Disposal Activity or Restructuring [Policy Text Block] Restructuring Charges Goodwill and Intangible Assets, Intangible Assets, Policy [Policy Text Block] Patent Costs Share-Based Payment Arrangement [Policy Text Block] Stock Based Compensation Income Tax, Policy [Policy Text Block] Income Taxes Comprehensive Income, Policy [Policy Text Block] Comprehensive Income (Loss) Earnings Per Share, Policy [Policy Text Block] Net Loss per Share New Accounting Pronouncements, Policy [Policy Text Block] Recently Issued Accounting Pronouncements Represents the tabular disclosure of estimated useful lives for property and equipment. Property, Plant and Equipment, Estimated Useful Lives [Table Text Block] Summary of estimated useful lives for property and equipment Schedule of Available-for-Sale Securities Reconciliation [Table Text Block] Schedule of marketable securities Tabular disclosure of the maturities of available-for-sale securities from cost basis to fair value. Schedule Of Available For Sale Securities Maturities Table Text Block Schedule of available-for-sale maturities Fair Value, by Balance Sheet Grouping [Table Text Block] Summary of fair value of the Company's financial assets Property, Plant and Equipment [Table Text Block] Summary of property and equipment Schedule of Accrued Liabilities [Table Text Block] Summary of accrued liabilities and other liabilities Lessee, Operating Lease, Liability, to be Paid, Maturity [Table Text Block] Schedule of future minimum lease payments under non-cancellable leases Share-Based Payment Arrangement, Option, Activity [Table Text Block] Summary of stock option activity Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block] Summary of stock based compensation expense recorded Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block] Summary of assumptions used in the Black Scholes option pricing model for stock options granted Schedule of Segment Reporting Information, by Segment [Table Text Block] Schedule of significant expense categories Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block] Summary of shares excluded from the computation of diluted net loss per share Schedule of Effective Income Tax Rate Reconciliation [Table Text Block] Summary of reconciliation of federal statutory income tax rate to the Company's effective income tax rate Schedule of Deferred Tax Assets and Liabilities [Table Text Block] Summary of components of deferred tax assets Subsequent Event [Table] Subsequent Event Type [Axis] Subsequent Event Type [Domain] Subsequent Event [Member] Subsequent Event Subsequent Event [Line Items] Subsequent Event Nature of the Business Number of new stock issued for reverse stock split fractional shares during the period. Stock Issued During Period, Reverse Stock Split Fractional Shares Reverse stock split shares The amount of cash, cash equivalents and marketable securities. Cash And Cash Equivalents and Marketable Securities At Carrying Value Cash, cash equivalents and marketable securities Number of Operating Segments Number of operating segment Number of Reportable Segments Number of reporting segment Property, Plant and Equipment [Table] Long-Lived Tangible Asset [Axis] Long-Lived Tangible Asset [Domain] Computer Equipment [Member] Computer equipment Equipment [Member] Equipment Furniture and Fixtures [Member] Furniture and fixtures Leasehold Improvements [Member] Leasehold improvements Property, Plant and Equipment [Line Items] Property, plant and equipment Property, Plant and Equipment, Useful Life Property, Plant and Equipment, Estimated Useful Lives Property, Plant, and Equipment, Useful Life, Term, Description [Extensible Enumeration] Represents the number of accredited financial institutions that are federally insured. Number Of Accredited Financial Institutions That Are Federally Insured Number of accredited financial institutions that are federally insured Asset Impairment Charges [Abstract] Property and Equipment, Net Impairment of Long-Lived Assets to be Disposed of Impairment loss recognized Not available. Preferred Stock Abstract Redeemable preferred stock: Preferred Stock Research and Development Expense [Abstract] Research and Development Costs, Including Clinical Trial Accruals and Acquired in Process Research and Development Represents the amount of accrued clinical trial expenses. Accrued Clinical Trial Expenses Accrued clinical trial costs Income Tax Uncertainties [Abstract] Income Taxes Unrecognized Tax Benefits, Income Tax Penalties and Interest Expense Uncertain income tax benefits, interest or penalties Disclosure of information about licensing agreements. License Agreement [Table] Scenario [Axis] Scenario [Domain] Represents information pertaining to initiation of the first Phase 1 clinical trial for SIM0505 has started. Upon Initiation Of First Phase 1 Clinical Trial For Sim 0505 [Member] Upon initiation of the first Phase 1 clinical trial for SIM0505 Represents information pertaining to initiation of the first Phase 2 clinical trial for SIM0505 has started. Upon Initiation Of The First Phase 2 Clinical Trial For SIM0505 [Member] Upon initiation of the first Phase 2 clinical trial for SIM0505 Represents information pertaining to achievement of development and regulatory milestone payments of Zaiming Product. Upon Achieving Development And Regulatory Milestone Of Zaiming Product [Member] Upon achieving development and regulatory milestone of Zaiming Product Represents information pertaining to achievement of development and regulatory milestone payments of NextCure Product. Upon Achieving Development And Regulatory Milestone Of NextCure Product [Member] Upon achieving development and regulatory milestone of NextCure Product Represents information pertaining to achievement of commercial sales-based milestone. Upon Achieving Commercial Sales-Based Milestone [Member] Upon achieving commercial sales-based milestone Statistical Measurement [Axis] Statistical Measurement [Domain] Maximum [Member] Maximum Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table. License Agreement [Line Items] License Agreement The amount of consideration for acquiring rights under the licensing agreements. Licensing Agreement, Consideration To Acquire Rights Consideration agreed The amount of cash outflow pertaining to upfront payment under the licensing agreements. Licensing Agreement, Upfront Cash Payment Upfront cash payment The amount payable upon qualifying event under the licensing agreement. Licensing Agreement, Amount Payable Consideration payable Aggregate value of common shares reserved for future issuance. Common Stock, Capital Shares Value Reserved for Future Issuance Value of stock agreed to be issued Amount of expense pertaining to rights under the licensing agreements. Licensing Agreement Expense License agreement expense The amount of milestone payments to be made upon achievement of events. Licensing Agreement, Milestone Payments Milestone payments Collaborative Arrangement and Arrangement Other than Collaborative [Table] Collaborative Arrangement and Arrangement Other than Collaborative [Axis] Collaborative Arrangement and Arrangement Other than Collaborative [Domain] Represents information pertaining to research and development collaboration agreement. Research Collaboration and Co-Development Agreement Research Collaboration and Co-Development Agreement Counterparty Name [Axis] Counterparty Name [Domain] Represents information pertaining to LigaChem Biosciences. LigaChem Biosciences LigaChem Biosciences Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] Collaboration Agreements Represents the maximum number of antibody drug conjugates to be developed. Maximum Number Of Antibody Drug Conjugates To Be Developed Maximum number of antibody drug conjugates to be developed Represents the collaboration agreements cost sharing percentage. Collaboration Agreements Cost Sharing Percentage Collaboration agreements cost sharing percentage (as a percent) The amount of collaborative arrangement reduction in expense. Collaborative Arrangement Reduction In Expense Amount Collaboration arrangement reduction in expenses Amount of additional receivable on finalization of costs sharing terms under collaborative agreements. Collaboration Agreements, Additional Receivable on Finalization of Cost Sharing Terms Additional receivable on collaboration agreements, finalization of cost sharing Debt Securities, Available-for-Sale [Table] Financial Instrument [Axis] Financial Instruments [Domain] Corporate Debt Securities [Member] Corporate bonds This category includes information about debt securities issued by the United States Department of the Treasury and backed by the United States government. Such securities primarily consist of treasury bills (short-term maturities - one year or less), treasury notes (intermediate term maturities - two to ten years), and treasury bonds (long-term maturities - ten to thirty years). This category also includes information about debt issued by US Government Corporations and Agencies. Investments in such US Government Corporations may include debt securities issued by the Government National Mortgage Association (Ginnie Mae) and by the Federal National Mortgage Association (Fannie Mae) and the Federal Home Loan Mortgage Corporation (Freddie Mac). U.S. Treasury and Government agencies U.S. Treasury and Government agencies Debt Securities, Available-for-Sale [Line Items] Investments Debt Securities, Available-for-Sale, Amortized Cost, Excluding Accrued Interest, before Allowance for Credit Loss Amortized Cost Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax Gross Unrealized Gain Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Loss, before Tax Gross Unrealized Loss Debt Securities, Available-for-Sale, Excluding Accrued Interest Estimated Fair Value Marketable Securities Debt Securities, Available-for-Sale, Realized Gain Gross realized gains Debt Securities, Available-for-Sale, Realized Loss Gross realized loss Number of debt securities being available for sales, whose loss position which was not in a continuous unrealized loss position for more than twelve months. Number Of Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, 12 Months or Less Number of investment whose position which was not in continuous unrealized loss position for more than twelve months Debt Securities, Available-for-Sale, Unrealized Loss Position Fair market value of investments in unrealized loss position Represents the total non-operating interest income. Interest Income Non Operating Interest income Available-for-Sale Securities, Debt Maturities [Abstract] Cost Maturities: Debt Securities, Available-for-Sale, Amortized Cost, Maturity, Allocated and Single Maturity Date, Year One Within 1 year Amortized cost of investment in debt security measured at fair value with change in fair value recognized in other comprehensive income (available-for-sale), with single maturity date and allocated without single maturity date, maturing after next fiscal year following current fiscal year. Excludes interim and annual periods when interim periods are reported from current statement of financial position date (rolling approach). Available For Sale Securities Debt Maturities Over One Year Amortized Cost Over 1 year Debt Securities, Available-for-Sale, Maturity, Allocated and Single Maturity Date, Amortized Cost Total investments available for sale Debt Securities, Available-for-Sale, Maturity, Allocated and Single Maturity Date, Fair Value [Abstract] Fair Value Maturities: Debt Securities, Available-for-Sale, Fair Value, Maturity, Allocated and Single Maturity Date, Year One Within 1 year Fair value of investment in debt security measured at fair value with change in fair value recognized in other comprehensive income (available-for-sale), with single maturity date and allocated without single maturity date, maturing after next fiscal year following current fiscal year. Available For Sale Securities Debt Maturities Over One Year Fair Value Over 1 year Debt Securities, Available-for-Sale, Maturity, Allocated and Single Maturity Date, Fair Value Total investments available for sale Fair Value, by Balance Sheet Grouping [Table] Cash and Cash Equivalents [Axis] Cash and Cash Equivalents [Domain] Money Market Funds [Member] Money market funds (cash equivalents) Measurement Basis [Axis] Portion at Fair Value Measurement [Member] Estimate of Fair Value Measurement [Member] Fair Value Fair Value Hierarchy and NAV [Axis] Fair Value Hierarchy and NAV [Domain] Fair Value, Inputs, Level 1 [Member] Quoted Prices in Active Markets (Level 1) Fair Value, Inputs, Level 2 [Member] Significant Other Observable Inputs (Level 2) Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items] Financial Instruments, Financial Assets, Balance Sheet Groupings [Abstract] Fair value of the Company's financial assets Cash and Cash Equivalents, Fair Value Disclosure Money market funds (cash equivalents) 1 Marketable Securities And Cash Equivalents Total financial assets Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Asset Transfers Into Level 3 Assets transferred into level 3 Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Asset, Transfers out of Level 3 Assets transferred out of level 3 Amounts of transfers of assets measured on a recurring basis out of Level 1 of the fair value hierarchy into Level 2. Fair Values Assets Level 1 To Level 2 Transfers Amount Assets transferred from level 1 to level 2 Amounts of transfers of assets measured on a recurring basis out of Level 2 of the fair value hierarchy into Level 1. Fair Values Assets Level 2 To Level 1 Transfers Amount Assets transferred from level 2 to level 1 Tangible research equipment. Research equipment Research equipment Property, Plant and Equipment, Net [Abstract] Property and Equipment, Net Property, Plant and Equipment, Gross Property and equipment, gross Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment Less: accumulated depreciation and amortization Depreciation, Depletion and Amortization Depreciation and amortization expense Employee-related Liabilities, Current Payroll and related benefits Carrying value as of the balance sheet date of obligations incurred through that date and payable for clinical trial costs. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer). Accrued Clinical Trial Costs, Current Clinical trial costs Carrying value as of the balance sheet date of obligations incurred through that date and payable for sponsored research expenses. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer). Accrued Sponsored Research Expense, Current Sponsored research Operating Lease, Liability, Current Lease liabilities, current portion Operating Lease, Liability, Current, Statement of Financial Position [Extensible Enumeration] Carrying value as of the balance sheet date of obligations incurred through that date and payable for milestone payments. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer). Accrued Milestone Payments, Current License payments Carrying value as of the balance sheet date of obligations incurred through that date and payable for operating expenses. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer). Accrued Operating Expenses, Current Operating expenses Other Liabilities, Current Other Lessee, Operating Lease, Renewal Term Lease extension period Lessee, Operating Lease, Existence of Option to Extend [true false] Operating Lease, Expense Operating lease expense Operating Lease, Payments Operating cash flows used for operating leases Operating Lease, Weighted Average Remaining Lease Term Weighted=average remaining lease term Operating Lease, Weighted Average Discount Rate, Percent Weighted average discount rate (as a percent) Lessee, Operating Lease, Liability, to be Paid, Fiscal Year Maturity [Abstract] Future minimum lease payments Lessee, Operating Lease, Liability, to be Paid, Year One 2026 Lessee, Operating Lease, Liability, to be Paid, Year Two 2027 Lessee, Operating Lease, Liability, to be Paid, Year Three 2028 Lessee, Operating Lease, Liability, to be Paid, Year Four 2029 Lessee, Operating Lease, Liability, to be Paid, Year Five 2030 Lessee, Operating Lease, Liability, to be Paid Total future minimum payments Lessee, Operating Lease, Liability, Undiscounted Excess Amount Less: present value discount Operating Lease, Liability Present value of lease liabilities Stock, Class of Stock [Table] Class of Stock [Line Items] Preferred stock Represents the number of votes per share. Number Of Votes Per Share Number of votes per share Common Stock, Dividends, Per Share, Declared Dividends declared Subsidiary or Equity Method Investee, Sale of Stock, Type [Table] Class of Warrant or Right [Axis] Class of Warrant or Right [Domain] Represents information pertaining to pre-funded warrants. Pre-Funded Warrants [Member] Pre-Funded Warrants Subsidiary, Sale of Stock [Line Items] Common Stock Shares Issued, Price Per Share purchase price, per share Class of Warrant or Right, Number of Securities Called by Warrants or Rights Number of warrants purchase Purchase price of each warrant issued under securities purchase agreement. Purchase Price Per Warrant Purchase price for warrant Class of Warrant or Right, Exercise Price of Warrants or Rights Exercise price of warrants Class of Warrant or Right, Outstanding Remaining outstanding balance of pre-funded warrants Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table] Plan Name [Axis] Plan Name [Domain] Represents information pertaining to 2015 omnibus incentive plan. 2015 Plan 2015 Plan Represents information pertaining to Omnibus Incentive 2019 Plan. Omnibus Incentive Plan Omnibus Incentive Plan Represents information pertaining to 2015 omnibus incentive plan and the information pertaining to 2019 Employee Stock Purchase Plan. 2015 Plan and 2019 Employee Stock Purchase Plan 2015 Plan and 2019 Employee Stock Purchase Plan Represents information pertaining to 2019 Employee Stock Purchase Plan. 2019 Employee Stock Purchase Plan 2019 Employee Stock Purchase Plan Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items] Restricted Common Stock Stock Based Compensation The increase in shares available for issuance as a percentage of number of shares of the company's common stock outstanding on December 31st of the preceding calendar year. Share Based Compensation Arrangement, Increase In Shares For Issuance As A Percentage Of Number Of Common Stock Outstanding Annual increase in number of share reserved for issuance (as percent) Common Stock, Capital Shares Reserved for Future Issuance Number of shares reserved for issuance under the plan Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Period Vesting period Period which an employee's right to exercise an award is no longer available. Share Based Compensation Arrangement By Share Based Payment Award Award Expiration Period Expiration period Share-Based Compensation Arrangement by Share-Based Payment Award, Shares Issued in Period Number of shares issued The threshold number of shares of the company's common stock available for issuance under the plan. Share Based Compensation Arrangement, Threshold Number Of Common Stock For Issuance Under The Plan Maximum annual increase in shares available for issuance under the plan Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding [Roll Forward] Number of Shares Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number Outstanding at the end (in shares) Outstanding at the beginning (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross Granted (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period Forfeitures (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Exercisable, Number Exercisable at the end (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Abstract] Weighted Average Exercise Price Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price Outstanding at the end (in dollars per share) Outstanding at the beginning (in dollars per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price Granted (in dollars per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price Exercised (in dollars per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price Forfeited (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Exercisable, Weighted Average Exercise Price Exercisable at the end (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Additional Disclosures [Abstract] Weighted Average Remaining Contractual Life (Years) And Aggregate Intrinsic Value Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term Outstanding (in years) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Exercisable, Weighted Average Remaining Contractual Term Exercisable at the end (in years) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value Outstanding at the end (in dollars) Outstanding at the beginning (in dollars) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Exercisable, Aggregate Intrinsic Value Exercisable at the end (in dollars) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value Weighted average grant date fair value per share of stock options granted Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period, Intrinsic Value Aggregate intrinsic value of stock options exercised Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested in Period, Fair Value Aggregate grant date fair value Share-Based Payment Arrangement, Additional Disclosure [Abstract] Share Based Compensation Expense Not Recognized Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount Unrecognized compensation cost Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition Compensation expense recognition period Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table] Statement of Income Location, Balance [Axis] Statement of Income Location, Balance [Domain] Research and Development Expense [Member] Research and development General and Administrative Expense [Member] General and administrative Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Line Items] Stock based compensation expense Share-Based Payment Arrangement, Expense Total stock-based compensation expense Minimum [Member] Minimum Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions and Methodology [Abstract] Fair value assumptions Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term Expected term Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Weighted Average Volatility Rate Expected volatility Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate Risk free interest rate Restructuring Cost [Table] Restructuring Type [Axis] Type of Restructuring [Domain] Employee Severance [Member] Employee severance Restructuring Cost and Reserve [Line Items] Restructuring and Asset Impairment Restructuring and Related Cost, Number of Positions Eliminated, Period Percent Percent of workforce reduction Payments for Restructuring Cash payments Restructuring Reserve Severance accrual Schedule of Segment Reporting Information, by Segment [Table] Segment Reporting Information [Line Items] Segment Information Segments [Axis] Segments [Domain] Represents the information pertaining to single reporting segment. Single Reporting Segment [Member] Single reporting segment Amount of expense for research and development, relating to employee costs. Research and Development Expense, Employee Costs Employee costs Amount of expense for research and development, relating to clinical product candidates. Research and Development Expense, Clinical Product Candidates Clinical product candidates Amount of expense for research and development, relating to non-clinical product candidates. Research and Development Expense, Nonclinical Product Candidates Nonclincal product candidates Amount of expense for research and development, relating to depreciation. Research and Development Expense, Depreciation Depreciation and amortization Other Research and Development Expense Other R&D General and Administrative Expense [Abstract] General and administrative expenses The expenses of managing and administering the affairs of an entity, including affiliates of the reporting entity, relating to employee costs. General and Administrative Expense, Employee Costs Employee costs The expenses of managing and administering the affairs of an entity, including affiliates of the reporting entity, relating to professional services. General and Administrative Expense, Professional Services Professional services The expenses of managing and administering the affairs of an entity, including affiliates of the reporting entity, relating to insurance services. General and Administrative Expense, Insurance Insurance Other General and Administrative Expense Other G&A Antidilutive Security, Excluded EPS Calculation [Table] Antidilutive Securities [Axis] Antidilutive Securities, Name [Domain] Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Antidilutive Securities Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount Antidilutive securities excluded from computation of diluted net loss per share Income Tax Expense (Benefit), Effective Income Tax Rate Reconciliation, Amount [Abstract] Effective Income Tax Rate Reconciliation at Federal Statutory Income Tax Rate, Amount Expected income tax benefit at the federal statutory rate Effective Income Tax Rate Reconciliation, State and Local Income Taxes, Amount State taxes, net of federal benefit Effective Income Tax Rate Reconciliation, Tax Credit, Research, Amount Research and development credit, net Effective Income Tax Rate Reconciliation, Other Adjustments, Amount Other Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Amount Change in valuation allowance Income Tax Expense (Benefit) Income Tax Expense (Benefit), Total Provision or benefit from income taxes Effective Income Tax Rate Reconciliation, Percent [Abstract] Reconciliation of federal statutory income tax rate to the Company's effective income tax rate Effective Income Tax Rate Reconciliation, at Federal Statutory Income Tax Rate, Percent Expected income tax benefit at the federal statutory rate (as a percent) Effective Income Tax Rate Reconciliation, State and Local Income Taxes, Percent State taxes, net of federal benefit (as a percent) Effective Income Tax Rate Reconciliation, Tax Credit, Research, Percent Research and development credit, net (as a percent) Percentage of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations attributable to research tax credit, net. Effective Income Tax Rate Reconciliation Tax Credits Research Net Research and development credit, net (as a percent) Effective Income Tax Rate Reconciliation, Nondeductible Expense, Percent Non-deductible items (as a percent) Effective Income Tax Rate Reconciliation, Other Adjustments, Percent Other (as a percent) Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Percent Change in valuation allowance (as a percent) Effective Income Tax Rate Reconciliation, Percent Total (as a percent) Effective tax rate (as a percent) Tax Jurisdiction of Domicile [Extensible Enumeration] Components of Deferred Tax Assets and Liabilities [Abstract] Principal components of the Company's deferred tax assets Deferred Tax Assets, Net [Abstract] Deferred tax assets: Deferred Tax Assets, Operating Loss Carryforwards Federal and state net operating loss carryforwards Deferred Tax Assets, Tax Credit Carryforwards, Research Research and development tax credits Amount before allocation of valuation allowances of deferred tax asset attributable to capitalized research and development costs. Deferred Tax Assets Capitalized Research And Development Capitalized R&D Costs Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from operating lease liabilities. Deferred Tax Assets Operating Lease Liabilities Operating lease liabilities Deferred Tax Assets, Tax Deferred Expense, Compensation and Benefits, Share-Based Compensation Cost Share-based compensation Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from reserves and accruals and amount, before allocation of valuation allowance, of deferred tax asset attributable to deductible temporary differences, classified as other. Deferred Tax Assets Tax Deferred Expense Reserves And Accruals And Other Accruals and other Deferred Tax Assets, Gross Gross deferred tax assets Deferred Tax Assets, Valuation Allowance Less: valuation allowance Deferred Tax Assets, Net of Valuation Allowance Total deferred tax assets Deferred Tax Liabilities, Net [Abstract] Deferred tax liabilities: Deferred Tax Liabilities, Leasing Arrangements Operating lease assets Deferred Tax Liabilities, Gross Gross deferred tax liabilities Deferred Tax Assets, Net Net deferred tax assets Valuation Allowance, Deferred Tax Asset, Increase (Decrease), Amount Increase in valuation allowance Deferred Tax Assets, Operating Loss Carryforwards, Domestic Federal net operating loss carryforwards Deferred Tax Assets, Operating Loss Carryforwards, State and Local State net operating loss carryforwards Deferred Tax Assets, Operating Loss Carryforwards, Not Subject to Expiration Federal net operating loss carryforwards that do not expire Amount before allocation of valuation allowances of deferred tax asset attributable to deductible domestic research and development tax credit carryforwards. Deferred Tax Assets, Tax Credit Carryforwards, Research And Development, Federal Federal research and development tax credit carryforwards Amount before allocation of valuation allowances of deferred tax asset attributable to deductible state research and development tax credit carryforwards. Deferred Tax Assets, Tax Credit Carryforwards, Research And Development, State State research and development tax credit carryforwards Unrecognized Tax Benefits Unrecognized income tax benefits Defined Contribution Plan, Employer Discretionary Contribution Amount Employer contributions amount