99900 - Disclosure - Standard And Custom Axis Domain Defaults link:presentationLink link:calculationLink link:definitionLink 00100 - Statement - BALANCE SHEETS link:presentationLink link:calculationLink link:definitionLink 00200 - Statement - STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS link:presentationLink link:calculationLink link:definitionLink 00400 - Statement - STATEMENTS OF CASH FLOWS link:presentationLink link:calculationLink link:definitionLink 40201 - Disclosure - Summary of Significant Accounting Policies - Restricted Cash (Details) link:presentationLink link:calculationLink link:definitionLink 40301 - Disclosure - Marketable Securities - (Details) link:presentationLink link:calculationLink link:definitionLink 40401 - Disclosure - Fair Value Measurements - (Details) link:presentationLink link:calculationLink link:definitionLink 40501 - Disclosure - Property and Equipment, Net - (Details) link:presentationLink link:calculationLink link:definitionLink 40601 - Disclosure - Accrued Liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 40802 - Disclosure - Commitments and Contingencies - Future Minimum Payments (Details) link:presentationLink link:calculationLink link:definitionLink 41401 - Disclosure - Income Taxes - Reconciliation (Details) link:presentationLink link:calculationLink link:definitionLink 41402 - Disclosure - Income Taxes - Deferred tax assets (Details) link:presentationLink link:calculationLink link:definitionLink 00090 - Document - Document and Entity Information link:presentationLink link:calculationLink link:definitionLink 00105 - Statement - BALANCE SHEETS - (Parenthetical) link:presentationLink link:calculationLink link:definitionLink 00300 - Statement - STATEMENTS OF STOCKHOLDERS EQUITY link:presentationLink link:calculationLink link:definitionLink 00305 - Statement - STATEMENTS OF STOCKHOLDERS EQUITY (Parenthetical) link:presentationLink link:calculationLink link:definitionLink 10301 - Disclosure - Marketable Securities link:presentationLink link:calculationLink link:definitionLink 10901 - Disclosure - Term Loan link:presentationLink link:calculationLink link:definitionLink 11001 - Disclosure - Preferred Stock link:presentationLink link:calculationLink link:definitionLink 11101 - Disclosure - Common Stock link:presentationLink link:calculationLink link:definitionLink 11201 - Disclosure - Stock-Based Compensation link:presentationLink link:calculationLink link:definitionLink 11301 - Disclosure - Net Loss per Share Attributable to Common Stockholders link:presentationLink link:calculationLink link:definitionLink 11401 - Disclosure - Income Taxes link:presentationLink link:calculationLink link:definitionLink 11501 - Disclosure - Employee Benefit Plan link:presentationLink link:calculationLink link:definitionLink 11601 - Disclosure - Subsequent Events link:presentationLink link:calculationLink link:definitionLink 30303 - Disclosure - Marketable Securities (Tables) link:presentationLink link:calculationLink link:definitionLink 31203 - Disclosure - Stock-Based Compensation (Tables) link:presentationLink link:calculationLink link:definitionLink 31303 - Disclosure - Net Loss per Share Attributable to Common Stockholders (Tables) link:presentationLink link:calculationLink link:definitionLink 31403 - Disclosure - Income Taxes (Tables) link:presentationLink link:calculationLink link:definitionLink 40101 - Disclosure - Nature of the Business and Basis of Presentation - Public Offerings and Common Stock (Details) link:presentationLink link:calculationLink link:definitionLink 40102 - Disclosure - Nature of the Business and Basis of Presentation - Liquidity (Details) link:presentationLink link:calculationLink link:definitionLink 40202 - Disclosure - Summary of Significant Accounting Policies - Property and Equipment (Details) link:presentationLink link:calculationLink link:definitionLink 40204 - Disclosure - Summary of Significant Accounting Policies - Recently Issued Accounting Pronouncements (Details) link:presentationLink link:calculationLink link:definitionLink 40701 - Disclosure - Former Agreement with Eli Lilly and Company (Details) link:presentationLink link:calculationLink link:definitionLink 40901 - Disclosure - Term Loan - Other (Details) link:presentationLink link:calculationLink link:definitionLink 41001 - Disclosure - Preferred Stock (Details) link:presentationLink link:calculationLink link:definitionLink 41101 - Disclosure - Common Stock (Details) link:presentationLink link:calculationLink link:definitionLink 41201 - Disclosure - Stock-Based Compensation - Stock options (Details) link:presentationLink link:calculationLink link:definitionLink 41202 - Disclosure - Stock-Based Compensation - Stock based compensation expense (Details) link:presentationLink link:calculationLink link:definitionLink 41203 - Disclosure - Stock-Based Compensation - Assumptions (Details) link:presentationLink link:calculationLink link:definitionLink 41204 - Disclosure - Stock-Based Compensation - Restricted Common Stock (Details) link:presentationLink link:calculationLink link:definitionLink 41301 - Disclosure - Net Loss per Share Attributable to Common Stockholders - Anti-dilutive effect (Details) link:presentationLink link:calculationLink link:definitionLink 41501 - Disclosure - Employee Benefit Plan (Details) link:presentationLink link:calculationLink link:definitionLink 41601 - Disclosure - Subsequent Events - (Details) link:presentationLink link:calculationLink link:definitionLink 10101 - Disclosure - Nature of the Business and Basis of Presentation link:presentationLink link:calculationLink link:definitionLink 10201 - Disclosure - Summary of Significant Accounting Policies link:presentationLink link:calculationLink link:definitionLink 10401 - Disclosure - Fair Value Measurements link:presentationLink link:calculationLink link:definitionLink 10501 - Disclosure - Property and Equipment, Net link:presentationLink link:calculationLink link:definitionLink 10601 - Disclosure - Accrued Liabilities link:presentationLink link:calculationLink link:definitionLink 10701 - Disclosure - Former Agreement with Eli Lilly and Company link:presentationLink link:calculationLink link:definitionLink 10801 - Disclosure - Commitments and Contingencies link:presentationLink link:calculationLink link:definitionLink 20202 - Disclosure - Summary of Significant Accounting Policies (Policies) link:presentationLink link:calculationLink link:definitionLink 30203 - Disclosure - Summary of Significant Accounting Policies (Tables) link:presentationLink link:calculationLink link:definitionLink 30403 - Disclosure - Fair Value Measurements (Tables) link:presentationLink link:calculationLink link:definitionLink 30503 - Disclosure - Property and Equipment, Net (Tables) link:presentationLink link:calculationLink link:definitionLink 30603 - Disclosure - Accrued Liabilities (Tables) link:presentationLink link:calculationLink link:definitionLink 30803 - Disclosure - Commitments and Contingencies (Tables) link:presentationLink link:calculationLink link:definitionLink 40203 - Disclosure - Summary of Significant Accounting Policies - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink 40801 - Disclosure - Commitments and Contingencies - Other (Details) link:presentationLink link:calculationLink link:definitionLink